Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586708 | 0.87 | LMNA (0.43) | LMNA | |
| SCHEMBL28451566 | 0.84 | LMNA (0.55) | LMNA | |
| SCHEMBL7075563 | 0.84 | LMNA (0.55) | LMNA | |
| SCHEMBL8622144 | 0.84 | LMNA (0.36) | LMNA | |
| SCHEMBL7764898 | 0.81 | LMNA (0.64) | LMNA | |
| SCHEMBL29084760 | 0.77 | LMNA (0.47) | LMNA | |
| SCHEMBL14181569 | 0.76 | LMNA (0.41) | LMNA | |
| SCHEMBL28551111 | 0.75 | LMNA (0.35) | LMNA | |
| SCHEMBL14334595 | 0.75 | LMNA (0.70) | LMNA | |
| SCHEMBL7050768 | 0.75 | LMNA (0.70) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100336800-C | Preparation method of S-N, N' -bis [ 2-hydroxy-1- (hydroxymethyl) ethyl ] -5- [ (2-hydroxy-1-oxopropyl) amino ] -2, 4, 6-triiodo-1, 3-benzenedicarboxamide | DIBRA SPA (IT) | 2007-09-12 | — | — | CN | disclosed |
| EP-1075462-B1 | PROCESS FOR THE PREPARATION OF S- N,N'- BIS[2- HYDROXY-1- (HYDROXYMETHYL) ETHYL]-5- [(2- HYDROXY-1- OXOPROPYL)- AMINO]- 2,4,6- TRIIODO- 1,3- BENZENEDICARBOXAMIDE | BRACCO IMAGING SPA (IT) | 2003-06-25 | — | — | EP | disclosed |
| CN-1302288-A | Method for preparing S-N, N' -bis [ 2-hydroxy-1- (hydroxymethyl) ethyl ] -5- [ (2-hydroxy-1-oxopropyl) amino ] -2, 4, 6-triiodo-1, S-benzenedicarboxamide | DIBRA SPA (IT) | 2001-07-04 | — | — | CN | disclosed |
| EP-1075462-A2 | PROCESS FOR THE PREPARATION OF S- N,N'- BIS[2- HYDROXY-1- (HYDROXYMETHYL) ETHYL]-5- [(2- HYDROXY-1- OXOPROPYL)- AMINO]- 2,4,6- TRIIODO- 1,3- BENZENEDICARBOXAMIDE | BRACCO IMAGING S.p.A. (IT) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999058494-A3 | PROCESS FOR THE PREPARATION OF S- N,N'- BIS[2- HYDROXY-1- (HYDROXYMETHYL) ETHYL]-5- [(2- HYDROXY-1- OXOPROPYL)- AMINO]- 2,4,6- TRIIODO- 1,3- BENZENEDICARBOXAMIDE | BRACCO INT BV (NL) | 2000-01-20 | — | — | WO | disclosed |
| WO-1999058494-A2 | PROCESS FOR THE PREPARATION OF S- N,N'- BIS[2- HYDROXY-1- (HYDROXYMETHYL) ETHYL]-5- [(2- HYDROXY-1- OXOPROPYL)- AMINO]- 2,4,6- TRIIODO- 1,3- BENZENEDICARBOXAMIDE | DIBRA S.P.A. (IT) | 1999-11-18 | — | — | WO | disclosed |