Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856191 | 0.89 | CCR1 (0.80) | CCR1KDM4EALDH1A1NPSR1 | |
| SCHEMBL2861171 | 0.88 | CCR1 (0.69) | CCR1KDM4EALDH1A1NPSR1 | |
| SCHEMBL2852896 | 0.87 | KDM4E (0.63) | CCR1KDM4EALDH1A1 | |
| SCHEMBL2856127 | 0.85 | CCR1 (0.64) | CCR1 | |
| SCHEMBL2857457 | 0.83 | CCR1 (0.49) | CCR1KDM4ENPSR1 | |
| SCHEMBL2857923 | 0.83 | CCR1 (0.66) | CCR1KDM4EALDH1A1NPSR1 | |
| SCHEMBL2852102 | 0.83 | ALDH1A1 (0.67) | CCR1KDM4EALDH1A1 | |
| SCHEMBL2858070 | 0.83 | CCR1 (0.57) | CCR1KDM4EALDH1A1 | |
| SCHEMBL2860195 | 0.82 | CCR1 (0.70) | CCR1KDM4EALDH1A1NPSR1 | |
| SCHEMBL2850548 | 0.82 | CCR1 (0.61) | CCR1KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |