Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056228 | 0.77 | — | — | |
| SCHEMBL13395692 | 0.76 | TP53 (0.38) | TP53TSHRSLC7A5 | |
| SCHEMBL18211564 | 0.76 | TP53 (0.45) | TP53TSHRSLC7A5 | |
| SCHEMBL17201497 | 0.76 | TP53 (0.45) | TP53TSHRSLC7A5 | |
| SCHEMBL17503658 | 0.72 | SLC7A5 (0.40) | TP53SLC7A5 | |
| SCHEMBL12951567 | 0.70 | TP53 (0.60) | TP53TSHRSLC7A5 | |
| SCHEMBL812149 | 0.69 | TP53 (0.57) | TP53TSHRSLC7A5 | |
| SCHEMBL13310465 | 0.69 | TP53 (0.57) | TP53TSHRSLC7A5 | |
| SCHEMBL812166 | 0.69 | TP53 (0.57) | TP53TSHRSLC7A5 | |
| SCHEMBL715386 | 0.69 | TP53 (0.57) | TP53TSHRSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645890-B | Synthesis method of 2-pyrazine carboxylic ester compound | 江苏广域化学有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-112645890-A | Synthesis method of 2-pyrazine carboxylic ester compound | 江苏广域化学有限公司 | 2021-04-13 | — | — | CN | disclosed |