Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18211564 | 1.00 | TP53 (0.45) | TP53ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL19229748 | 0.78 | TP53 (0.32) | TP53 | |
| SCHEMBL10439669 | 0.77 | ALDH1A1 (0.39) | TP53ALDH1A1MAPTPTGS1TSHR | |
| SCHEMBL13798808 | 0.76 | TP53 (0.30) | TP53 | |
| SCHEMBL28551502 | 0.76 | TP53 (0.43) | TP53SLC7A5TSHR | |
| SCHEMBL12666946 | 0.76 | ALDH1A1 (0.32) | TP53ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL13203564 | 0.76 | TP53 (0.30) | TP53 | |
| SCHEMBL7123845 | 0.74 | TSHR (0.50) | TP53ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL7877645 | 0.74 | TP53 (0.40) | TP53ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL2464055 | 0.74 | TP53 (0.40) | TP53ALDH1A1MAPTPTGS1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-05 | — | — | US | disclosed |
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | UNITED STATES DEPARTMENT OF ENERGY | 2019-11-14 | — | — | US | disclosed |
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | UNITED STATES DEPARTMENT OF ENERGY | 2019-11-14 | — | — | US | disclosed |
| US-10233431-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-03-19 | — | — | US | disclosed |
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | COASY, FASN, DHPS | TP53 4456/4885ALDH1A1 1555/4885MAPT 4148/4885 |
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | COASY, FASN, DHPS | TP53 4456/4885ALDH1A1 1555/4885MAPT 4148/4885 |
| US-10233431-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | COASY, FASN, DHPS | TP53 4456/4885ALDH1A1 1555/4885MAPT 4148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.