Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.50 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.50 |
| ▸ | FGR | P09769 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HBB | P68871 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27496947 | 0.88 | MAOA (0.53) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| Hydrochloric Acid SCHEMBL11262220 | 0.80 | MAOA (0.50) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| SCHEMBL12310492 | 0.80 | MAOA (0.50) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| SCHEMBL27787302 | 0.78 | MAPT (0.63) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| SCHEMBL7759083 | 0.78 | MAPT (0.59) | MAPTMAPK1SMN1; SMN2PKMADORA2A | |
| SCHEMBL10613217 | 0.76 | ADORA2A (0.61) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| SCHEMBL27849249 | 0.76 | MAOA (0.53) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| SCHEMBL12310536 | 0.76 | MAOA (0.46) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| SCHEMBL11574466 | 0.75 | MAPT (0.56) | MAPTMAPK1SMN1; SMN2PKMMAOA | |
| SCHEMBL12310564 | 0.75 | MAOA (0.51) | MAPTMAPK1SMN1; SMN2PKMMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017109182-A1 | COMPOSITION COMPRISING AT LEAST TWO DIFFERENT STARCHES AND A COLOURING AGENT | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| US-9554977-B2 | Triaromatic azomethine direct dyes, dye composition comprising at least one such dye, method of implementation and use | L'OREAL (FR) | 2017-01-31 | — | — | US | disclosed |
| US-9439844-B2 | Tri-aromatic azomethine direct dyes comprising at least one unit derived from resorcinol, dyeing composition, method and use | L'OREAL (FR) | 2016-09-13 | — | — | US | disclosed |
| US-9233057-B2 | Particular quinone direct dyes, dye composition comprising at least one such dye, implementation process therefor and use thereof | L'OREAL (FR) | 2016-01-12 | — | — | US | disclosed |
| US-9226883-B2 | Particular azomethine direct dyes, dye composition comprising at least one such compound, implementation process therefore and use thereof | L'OREAL (FR) | 2016-01-05 | — | — | US | disclosed |
| US-20150320660-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2015-11-12 | — | — | US | disclosed |
| WO-2015063125-A1 | EXPANDED DYEING COMPOSITION COMPRISING AN INERT GAS, A NON-VOLATILE ALKALINE AGENT AND A DYE | L'OREAL (FR) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015063122-A1 | EXPANDED DYEING COMPOSITION COMPRISING AN INERT GAS, AN OXIDATION DYE AND AN OXYALKYLENATED NONIONIC SURFACTANT | L'OREAL (FR) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015063124-A1 | DYEING METHOD EMPLOYING AN EXPANDED OXIDIZING COMPOSITION | L'OREAL (FR) | 2015-05-07 | — | — | WO | disclosed |
| US-20150027483-A1 | TRI-AROMATIC AZOMETHINE DIRECT DYES COMPRISING AT LEAST ONE UNIT DERIVED FROM RESORCINOL, DYEING COMPOSITION, METHOD AND USE | L'OREAL (FR) | 2015-01-29 | — | — | US | disclosed |
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | L'OREAL (FR) | 2015-01-01 | — | — | US | disclosed |
| US-20140360523-A1 | PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | L'OREAL (FR) | 2014-12-11 | — | — | US | disclosed |
| WO-2014131872-A2 | COSMETIC COMPOSITION IN THE FORM OF AN OIL-IN-WATER NANOEMULSION FOR THE DIRECT DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2014-09-04 | — | — | WO | disclosed |
| CN-102821738-A | Hair treatment process using a direct emulsion comprising an oxidizing agent and a direct emulsion containing an alkaline agent | OREAL | 2012-12-12 | — | — | CN | disclosed |
| WO-2010142776-A1 | N-OXIDIZED AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142777-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |
| CN-101909587-A | Composition for the oxidation dyeing of human keratin fibres comprising a fatty alcohol, a fatty ester and a cationic surfactant, method and device for using same | OREAL | 2010-12-08 | — | — | CN | disclosed |
| EP-2170260-A1 | AZO DERIVATIVES CONTAINING A PYRAZOLINONE UNIT FOR DYEING KERATIN FIBRES | L'Oreal (FR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009000753-A1 | AZO DERIVATIVES CONTAINING A PYRAZOLINONE UNIT FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320660-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | KRT18, MKI67, CDC73 | MAPT 469/4885MAPK1 1455/4885SMN1; SMN2 4876/4885 |
| US-20140360523-A1 | PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | KRT18, SQOR, NDUFB7 | MAPT 255/4885MAPK1 545/4885SMN1; SMN2 4815/4885 |
| US-20150027483-A1 | TRI-AROMATIC AZOMETHINE DIRECT DYES COMPRISING AT LEAST ONE UNIT DERIVED FROM RESORCINOL, DYEING COMPOSITION, METHOD AND USE | KRT18, IK, MKI67 | MAPT 132/4885MAPK1 1553/4885SMN1; SMN2 4856/4885 |
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | KRT18, IK, MKI67 | MAPT 755/4885MAPK1 1086/4885SMN1; SMN2 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.