Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL27606425 | 0.96 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL1793735 | 0.96 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL7455556 | 0.93 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL5249319 | 0.93 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL29231 | 0.93 | — | — | |
| Glycerin SCHEMBL8773344 | 0.93 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL2553942 | 0.93 | LMNA (0.75) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL23630291 | 0.89 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL8003351 | 0.89 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 | |
| Glycerin SCHEMBL17256232 | 0.89 | LMNA (0.69) | LMNAALDH1A1TSHRTHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107467613-B | Porous silica gel microspheres and application thereof in preparation of meat flavor essence | 浙江顶味食品有限公司 | 2021-03-02 | — | — | CN | disclosed |