SCHEMBL31482437

SCHEMBL31482437

c1ccc(-c2ccc(-c3ccccc3)c(-c3cn[nH]c3)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT2 P31751 3/20 0.63
AKT1 P31749 1/20 0.63
FEN1 P39748 2/20 0.49
CLK2 P49760 3/20 0.48
CLK4 Q9HAZ1 3/20 0.48
CLK1 P49759 2/20 0.48
HIPK1 Q86Z02 2/20 0.48
HIPK2 Q9H2X6 2/20 0.48
HIPK3 Q9H422 2/20 0.48
LRRK2 Q5S007 1/20 0.47
ROCK2 O75116 2/20 0.45
DYRK2 Q92630 2/20 0.45
DYRK3 O43781 1/20 0.45
CLK3 P49761 1/20 0.45
GSK3B P49841 1/20 0.45
CDK5 Q00535 1/20 0.45
DYRK1A Q13627 1/20 0.45
CDK5R1 Q15078 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
FYN P06241 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28552255 0.85 AKT2 (0.72) AKT2AKT1FEN1CLK2CLK4
SCHEMBL21142239 0.84 AKT2 (0.49) AKT2AKT1FEN1CLK2CLK4
SCHEMBL21142037 0.83 AKT2 (0.59) AKT2AKT1FEN1CLK2CLK4
SCHEMBL21142034 0.83 AKT2 (0.59) AKT2AKT1FEN1CLK2CLK4
SCHEMBL21142530 0.81 LRRK2 (0.47) AKT2AKT1FEN1CLK2CLK4
SCHEMBL16872766 0.81 AKT2 (0.95) AKT2AKT1CLK2CLK4CLK1
SCHEMBL1163770 0.81 AKT1 (0.51) AKT2AKT1FEN1CLK2CLK4
SCHEMBL22636741 0.80 AKT2 (0.59) AKT2AKT1FEN1CLK2CLK4
SCHEMBL29430626 0.80 AKT2 (0.59) AKT2AKT1FEN1CLK2CLK4
SCHEMBL28731972 0.80 ROCK2 (0.51) AKT2AKT1ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119746640-A Composite hollow fiber nanofiltration membrane and preparation method and application thereof 江苏赛诺膜分离科技有限公司 2025-04-04 CN claimed
CN-119746640-A Composite hollow fiber nanofiltration membrane and preparation method and application thereof 江苏赛诺膜分离科技有限公司 2025-04-04 CN disclosed
CN-119746640-A Composite hollow fiber nanofiltration membrane and preparation method and application thereof 江苏赛诺膜分离科技有限公司 2025-04-04 CN disclosed