Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369997 | 0.84 | LMNA (0.54) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL397856 | 0.80 | ALDH1A1 (0.49) | GAAMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL395708 | 0.79 | ALDH1A1 (0.54) | GAAMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL16095530 | 0.77 | MAPT (0.58) | GAAMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL398152 | 0.75 | LMNA (0.46) | GAAMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL398048 | 0.73 | ALDH1A1 (0.48) | GAAMAPTKMT2AMEN1RECQL | |
| SCHEMBL11215385 | 0.72 | GAA (0.51) | GAAMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL4804000 | 0.71 | SLC9A1 (0.45) | GAAMAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL28087088 | 0.71 | LMNA (0.47) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28087089 | 0.71 | SMN1; SMN2 (0.49) | GAAMAPTMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501099-B | Modulators of ATP-binding cassette transporters | 沃泰克斯药物股份有限公司 | 2021-03-19 | — | — | CN | disclosed |