Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 13/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.42 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848347 | 0.88 | GAA (0.51) | CCR1MALT1CYP1A2CYP3A4HPGD | |
| SCHEMBL2859043 | 0.86 | CCR1 (0.62) | CCR1MALT1HPGDMAPK14 | |
| SCHEMBL2860320 | 0.86 | CCR1 (0.52) | CCR1MALT1 | |
| SCHEMBL2859287 | 0.85 | TSHR (0.40) | CCR1MALT1 | |
| SCHEMBL2860444 | 0.84 | CCR1 (0.60) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2857636 | 0.83 | KDM4E (0.61) | CCR1HPGDDDR1MAPK11MAPK14 | |
| SCHEMBL2850536 | 0.82 | CCR1 (0.52) | CCR1MALT1HPGDDDR1MAPK11 | |
| SCHEMBL2854304 | 0.81 | NPC1 (0.49) | CCR1HPGDDDR1MAPK11MAPK14 | |
| SCHEMBL2854425 | 0.79 | CCR1 (0.60) | CCR1HPGDDDR1MAPK11MAPK14 | |
| SCHEMBL2860317 | 0.78 | CCR1 (0.62) | CCR1HPGDDDR1MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |