Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.62 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860320 | 0.93 | CCR1 (0.52) | CCR1ALDH1A1LMNAMALT1 | |
| SCHEMBL2848347 | 0.91 | GAA (0.51) | CCR1ALDH1A1HPGDMAPK14MALT1 | |
| SCHEMBL2855247 | 0.86 | CCR1 (0.49) | CCR1HPGDMAPK14MALT1 | |
| SCHEMBL2850470 | 0.85 | CCR1 (0.49) | CCR1ATG4BALDH1A1MAPK14 | |
| SCHEMBL2858942 | 0.84 | CCR1 (0.82) | CCR1 | |
| SCHEMBL2854304 | 0.83 | NPC1 (0.49) | CCR1ALDH1A1LMNAHPGDMAPK14 | |
| SCHEMBL2859642 | 0.83 | CCR1 (0.73) | CCR1ALDH1A1HPGDMAPK14 | |
| SCHEMBL5676581 | 0.83 | CCR1 (0.60) | CCR1MALT1 | |
| SCHEMBL2860195 | 0.81 | CCR1 (0.70) | CCR1ALDH1A1LMNAHPGD | |
| SCHEMBL2859008 | 0.80 | LMNA (0.66) | CCR1ATG4BLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |