Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 10/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559641 | 0.92 | HCAR3 (0.50) | HCAR3NAMPTMMEPPARGACHE | |
| SCHEMBL28559617 | 0.89 | PPARG (0.51) | HCAR3PPARG | |
| SCHEMBL16713328 | 0.83 | NR1H4 (0.51) | PPARGACHE | |
| SCHEMBL14977445 | 0.83 | PPARG (0.47) | PPARGACHE | |
| SCHEMBL16125425 | 0.83 | PPARG (0.53) | PPARGACHE | |
| SCHEMBL14977644 | 0.82 | PPARG (0.50) | PPARGACHE | |
| SCHEMBL16125516 | 0.80 | PPARG (0.49) | PPARGACHE | |
| SCHEMBL16125522 | 0.80 | PPARG (0.48) | PPARGACHE | |
| SCHEMBL16713349 | 0.80 | NR1H4 (0.51) | PPARGACHECDK9 | |
| SCHEMBL14120788 | 0.79 | PPARG (0.58) | PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434789-B | Benzotriazole derivatives, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2021-04-13 | — | — | CN | disclosed |