Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552677 | 0.92 | HCAR3 (0.62) | HCAR3NAMPTACHEMMEPPARG | |
| SCHEMBL28559617 | 0.88 | PPARG (0.51) | HCAR3PPARG | |
| SCHEMBL16713333 | 0.84 | BRD4 (0.49) | ACHEPPARGSMN1; SMN2 | |
| SCHEMBL16125422 | 0.84 | AGTR1 (0.44) | ACHEPPARGMEN1KMT2ASLC6A4 | |
| SCHEMBL16125424 | 0.83 | PPARG (0.47) | ACHEPPARGMEN1KMT2ARAB9A | |
| SCHEMBL16125427 | 0.82 | PPARG (0.45) | ACHEPPARGMEN1KMT2ARAB9A | |
| SCHEMBL15687303 | 0.81 | HCAR3 (0.74) | HCAR3NAMPTMAPK10MMELMNA | |
| SCHEMBL16713343 | 0.80 | BRD4 (0.53) | ACHESMN1; SMN2 | |
| SCHEMBL14121297 | 0.79 | PPARG (0.56) | ACHEPPARG | |
| SCHEMBL14121083 | 0.78 | PPARG (0.56) | ACHEPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434789-B | Benzotriazole derivatives, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2021-04-13 | — | — | CN | disclosed |