Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549063 | 0.82 | LDHA (0.46) | LDHAACACBELANEHTTF2RL1 | |
| SCHEMBL28558904 | 0.81 | LDHA (0.49) | LDHAPPARGPPARAACACBALDH1A1 | |
| SCHEMBL28558905 | 0.81 | LDHA (0.49) | LDHAPPARGPPARAACACBALDH1A1 | |
| SCHEMBL28558404 | 0.78 | ALDH1A1 (0.36) | LDHAPPARGPPARASCN9AACACB | |
| SCHEMBL29168113 | 0.78 | CTSL (0.44) | PPARGPPARASCN9A | |
| SCHEMBL29168078 | 0.76 | PPARG (0.41) | PPARGPPARASCN9AALDH1A1HTT | |
| SCHEMBL29168013 | 0.74 | SCN9A (0.32) | SCN9A | |
| SCHEMBL28912150 | 0.74 | LDHA (0.42) | LDHAACACBALDH1A1HTT | |
| SCHEMBL20415891 | 0.73 | PPARG (0.53) | PPARGPPARAALDH1A1 | |
| SCHEMBL28552849 | 0.73 | PPARG (0.53) | PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |