Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626057 | 0.81 | BCHE (0.38) | NOTUMBCHEACHEKDM4EMEN1 | |
| SCHEMBL18403202 | 0.76 | PNMT (0.53) | NOTUMACHEPNMTKDM4EMEN1 | |
| SCHEMBL5754293 | 0.73 | PNMT (0.55) | NOTUMPNMTHTT | |
| SCHEMBL29383544 | 0.73 | ALDH1A1 (0.39) | PNMTCYP1A2CYP2C19HTTKMT2A | |
| SCHEMBL2468219 | 0.73 | ALDH1A1 (0.39) | PNMTCYP1A2CYP2C19HTTKMT2A | |
| SCHEMBL29269316 | 0.72 | HPRT1 (0.50) | NOTUMBCHEACHEKDM4EMEN1 | |
| SCHEMBL29974199 | 0.72 | NOTUM (0.40) | NOTUMBCHEACHEPARP10PARP11 | |
| SCHEMBL3884626 | 0.72 | NOTUM (0.40) | NOTUMBCHEACHEPARP10PARP11 | |
| SCHEMBL582334 | 0.69 | NOTUM (0.46) | NOTUMBCHEACHEKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8013061 | 0.68 | NOTUM (0.44) | NOTUMBCHEACHEKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114106185-A | anti-HER 2 antibodies and immunoconjugates | 基因泰克公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-107001479-B | anti-HER 2 antibodies and immunoconjugates | 基因泰克公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-107001465-B | anti-CLL-1 antibodies and immunoconjugates | 基因泰克公司 | 2020-12-11 | — | — | CN | disclosed |