SCHEMBL2855513

SCHEMBL2855513

COc1ccc(-n2nc(Oc3cccnc3Br)oc2=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.55
FAAH O00519 1/20 0.55
ABHD16A O95870 1/20 0.50
ADORA3 P0DMS8 1/20 0.40
ADORA1 P30542 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2847268 0.76 ABHD16A (0.61) MGLLFAAHABHD16A
SCHEMBL2853266 0.74 MGLL (0.64) MGLLFAAHABHD16A
SCHEMBL6552566 0.71 MGLL (1.00) MGLLFAAHABHD16A
Hydrochloric Acid SCHEMBL3458788 0.71 MGLL (0.47) MGLLFAAH
SCHEMBL3458114 0.71 MGLL (0.55) MGLLFAAHABHD16A
SCHEMBL2233598 0.70 ABHD16A (0.72) MGLLFAAHABHD16A
SCHEMBL2826312 0.70 MGLL (0.55) MGLLFAAHABHD16A
SCHEMBL2701389 0.69 MGLL (0.53) MGLLFAAHABHD16A
SCHEMBL2701805 0.69 MGLL (0.53) MGLLFAAHABHD16A
SCHEMBL2856529 0.69 MGLL (0.67) MGLLFAAHABHD16A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2238131-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL - Portela & Ca., S.A. (PT) 2010-10-13 EP disclosed
WO-2009084970-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL-PORTELA & COMPANHIA, S.A. (PT) 2009-07-09 WO disclosed