Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.57 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044439 | 0.90 | MGLL (0.78) | MGLLFAAHNPBWR1ABHD16A | |
| SCHEMBL2854103 | 0.86 | FAAH (0.53) | MGLLFAAHNPBWR1ABHD16AMCHR1 | |
| SCHEMBL2233406 | 0.86 | ABHD16A (0.72) | MGLLFAAHNPBWR1ABHD16A | |
| SCHEMBL3458114 | 0.85 | MGLL (0.55) | MGLLFAAHNPBWR1ABHD16ANPSR1 | |
| SCHEMBL7044899 | 0.83 | MGLL (0.59) | MGLLFAAHNPBWR1ABHD16AMCHR1 | |
| SCHEMBL2828663 | 0.80 | MGLL (0.49) | MGLLFAAHNPBWR1ABHD16AMCHR1 | |
| SCHEMBL7046287 | 0.78 | MGLL (0.57) | MGLLFAAHNPBWR1ABHD16AALDH1A1 | |
| SCHEMBL6552566 | 0.78 | MGLL (1.00) | MGLLFAAHABHD16A | |
| SCHEMBL2702430 | 0.77 | MGLL (0.52) | MGLLFAAHNPBWR1ABHD16A | |
| SCHEMBL10825959 | 0.77 | NOTUM (0.55) | MGLLFAAHNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |