SCHEMBL28555151

SCHEMBL28555151

NC(=O)OC(CC1CCCCC1)C(=O)NCC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.47
CTSS P25774 2/20 0.47
CTSB P07858 1/20 0.47
CTSK P43235 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
METAP2 P50579 1/20 0.45
METAP1 P53582 1/20 0.45
CHRNB2 P17787 2/20 0.44
CHRNB4 P30926 2/20 0.44
CHRNA3 P32297 2/20 0.44
CHRNA4 P43681 2/20 0.44
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28349261 0.82 KLK7 (0.54) RAB9AMETAP2METAP1MMP1MMP2
SCHEMBL29052587 0.74 ALDH1A1 (0.42) CTSLCTSSCTSBCTSKMETAP2
SCHEMBL29052588 0.74 ALDH1A1 (0.42) CTSLCTSSCTSBCTSKMETAP2
SCHEMBL15989231 0.71 SMN1; SMN2 (0.52) CTSLCTSSCTSBCTSKSMN1; SMN2
SCHEMBL15989250 0.71 SMN1; SMN2 (0.52) CTSLCTSSCTSBCTSKSMN1; SMN2
SCHEMBL7277209 0.69 SMN1; SMN2 (0.51) SMN1; SMN2GAARAB9AMETAP2METAP1
SCHEMBL23023336 0.69 SMN1; SMN2 (0.74) SMN1; SMN2GAAHTTRAB9ARXFP1
SCHEMBL4826832 0.67 SMN1; SMN2 (0.53) SMN1; SMN2GAAHTTRAB9ARXFP1
SCHEMBL12831363 0.67 CTSL (0.70) CTSLCTSSCTSBCTSKMETAP2
SCHEMBL28554262 0.66 MEN1 (0.58) SMN1; SMN2HTTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112679483-A Preparation of guanidyl pentanamide derivative and application of guanidyl pentanamide derivative as antiviral drug 武城县人民医院 2021-04-20 CN claimed
CN-112679483-A Preparation of guanidyl pentanamide derivative and application of guanidyl pentanamide derivative as antiviral drug 武城县人民医院 2021-04-20 CN disclosed