Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293935 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7759502 | 0.71 | HPGD (0.57) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14074319 | 0.71 | GSK3B (0.50) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14523607 | 0.71 | GSK3B (0.50) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9740119 | 0.71 | USP30 (0.44) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| Cyclohexanol SCHEMBL28313927 | 0.70 | PKM (0.55) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28625425 | 0.70 | KMT2A (0.53) | SMN1; SMN2KMT2ANPC1RAB9APKM | |
| SCHEMBL28625426 | 0.70 | KMT2A (0.53) | SMN1; SMN2KMT2ANPC1RAB9APKM | |
| SCHEMBL28349261 | 0.69 | KLK7 (0.54) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL28555151 | 0.69 | CTSL (0.47) | SMN1; SMN2RAB9AGAACYP1A2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |