SCHEMBL2855533

SCHEMBL2855533

CCCOC(CC=O)OCCC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2850575 0.86 TSHR (0.39) ALDH1A1CA1CA2TSHR
SCHEMBL11647164 0.80 ALDH1A1 (0.33) ALDH1A1MAPK1TDP1TSHR
SCHEMBL440377 0.79 THRB (0.38) ALDH1A1MAPK1TDP1
SCHEMBL2927511 0.78
SCHEMBL3822689 0.77 THRB (0.36) ALDH1A1MAPK1TDP1
SCHEMBL11451477 0.77 THRB (0.36) ALDH1A1MAPK1TDP1
SCHEMBL9940198 0.76 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11384604 0.76 ALDH1A1 (0.31) ALDH1A1
SCHEMBL2854282 0.76 ALDH1A1 (0.42) ALDH1A1CA1CA2TSHR
SCHEMBL9047764 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1973006-B Single-component system based on co-reactive latex, preparation method and use in the field of formol-free coatings ARKEMA 2010-11-10 CN claimed
EP-1778804-B1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2010-01-20 EP claimed
EP-1773840-B1 SUBSTITUTED PYRIDO[3',2':4,5]THIENO[3,2-D]PYRIMIDINES AND PYRIDO[3',2':4,5]FURO[3,2-D]-PYRIMIDINES FOR USE AS INHIBITORS OF PDA-4 AND/OR TNF-ALPHA RELEASE MEDICINES CO LEIPZIG GMBH (DE) 2010-01-20 EP claimed
US-20080028982-A1 Single-Component System Based On Co-Reactive Latex, Preparation Method And Use In The Field Of Formol-Free Coatings VERGE CHRISTOPHE 2008-02-07 US claimed
CN-1973006-A Single-component system based on co-reactive latex, preparation method and use in the field of formol-free coatings ARKEMA (FR) 2007-05-30 CN claimed
EP-1778804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS Arkema France (FR) 2007-05-02 EP claimed
EP-1623987-A1 Fused pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and pyrido[3',2':4,5]furo[3,2-d]pyrimidines Curacyte Discovery GmbH (DE) 2006-02-08 EP claimed
WO-2006010804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2006-02-02 WO claimed
EP-1619196-A1 Substituted Pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and Pyrido[3',2':4,5]furo[3,2-d]-pyrimidines for use as inhibitors of PDA-4 and/or TNF-alpha release Curacyte Discovery GmbH (DE) 2006-01-25 EP claimed
CN-1973006-B Single-component system based on co-reactive latex, preparation method and use in the field of formol-free coatings ARKEMA 2010-11-10 CN disclosed
EP-1778804-B1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2010-01-20 EP disclosed
EP-1773840-B1 SUBSTITUTED PYRIDO[3',2':4,5]THIENO[3,2-D]PYRIMIDINES AND PYRIDO[3',2':4,5]FURO[3,2-D]-PYRIMIDINES FOR USE AS INHIBITORS OF PDA-4 AND/OR TNF-ALPHA RELEASE MEDICINES CO LEIPZIG GMBH (DE) 2010-01-20 EP disclosed
US-20080028982-A1 Single-Component System Based On Co-Reactive Latex, Preparation Method And Use In The Field Of Formol-Free Coatings VERGE CHRISTOPHE 2008-02-07 US disclosed
CN-1973006-A Single-component system based on co-reactive latex, preparation method and use in the field of formol-free coatings ARKEMA (FR) 2007-05-30 CN disclosed
EP-1778804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS Arkema France (FR) 2007-05-02 EP disclosed
EP-1623987-A1 Fused pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and pyrido[3',2':4,5]furo[3,2-d]pyrimidines Curacyte Discovery GmbH (DE) 2006-02-08 EP disclosed
WO-2006010804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2006-02-02 WO disclosed
EP-1619196-A1 Substituted Pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and Pyrido[3',2':4,5]furo[3,2-d]-pyrimidines for use as inhibitors of PDA-4 and/or TNF-alpha release Curacyte Discovery GmbH (DE) 2006-01-25 EP disclosed