SCHEMBL440377

SCHEMBL440377

CCOC(CC=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11451477 0.97 THRB (0.36) THRBLMNAALDH1A1MAPK1TDP1
SCHEMBL3822689 0.97 THRB (0.36) THRBLMNAALDH1A1MAPK1TDP1
SCHEMBL2855533 0.79 ALDH1A1 (0.33) ALDH1A1MAPK1TDP1
SCHEMBL28908691 0.78 LMNA (0.43) THRBLMNAALDH1A1MAPK1TDP1
SCHEMBL12442358 0.76
SCHEMBL4967277 0.76
SCHEMBL2850575 0.75 TSHR (0.39) ALDH1A1
SCHEMBL27700346 0.74 THRB (0.40) THRBLMNA
SCHEMBL9644124 0.74
SCHEMBL7328517 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105111214-A Preparation method of pemetrexed disodium UNIV JIANGXI AGRICULTURAL 2015-12-02 CN claimed
CN-101376708-B Method for synthesizing polyalkyl ether polymer with as propanal group as end group INST PROCESS ENG CAS 2010-12-08 CN claimed
CN-1973006-B Single-component system based on co-reactive latex, preparation method and use in the field of formol-free coatings ARKEMA 2010-11-10 CN claimed
EP-1778804-B1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2010-01-20 EP claimed
CN-101376708-A Method for synthesizing polyalkyl ether polymer with as propanal group as end group INST PROCESS ENG CAS (CN) 2009-03-04 CN claimed
US-20080028982-A1 Single-Component System Based On Co-Reactive Latex, Preparation Method And Use In The Field Of Formol-Free Coatings VERGE CHRISTOPHE 2008-02-07 US claimed
CN-1973006-A Single-component system based on co-reactive latex, preparation method and use in the field of formol-free coatings ARKEMA (FR) 2007-05-30 CN claimed
EP-1778804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS Arkema France (FR) 2007-05-02 EP claimed
WO-2006010804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2006-02-02 WO claimed
WO-1992018640-A1 ENZYMATIC METHOD FOR PREPARING ENANTIOMER- AND DIASTERIOMER-PURE KETOSES AND THEIR 1-ORTHOPHOSPHATE ESTERS BOEHRINGER MANNHEIM GMBH (DE) 1992-10-29 WO claimed
CN-109824591-A A kind of synthetic method of chloro- 6,7- dihydro -5H- cyclopentano [b] pyridine -5- ketone of 3- 药雅科技(上海)有限公司 2019-05-31 CN disclosed
EP-2690084-B1 METHOD FOR PRODUCING HYDROXYL GROUP-CONTAINING ACETAL COMPOUND NOF CORP (JP) 2017-04-19 EP disclosed
EP-1538145-B1 PROCESS FOR PRODUCTION OF PHENOXY-SUBSTITUTED 2-PYRIDONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2016-02-17 EP disclosed
CN-105111214-A Preparation method of pemetrexed disodium UNIV JIANGXI AGRICULTURAL 2015-12-02 CN disclosed
CN-103443063-B For the production of the method for hydroxyl acetal compound NOF CORP. (JP) 2015-11-25 CN disclosed
WO-1991009016-A2 HALOPHENYL SUBSTITUTED HETEROCYCLIC DERIVATIVES MERCK PATENT GMBH (DE) 1991-06-27 WO disclosed
EP-0223588-B1 PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-12 EP disclosed
US-4834772-A Battery electrolyte CAPE COD RESEARCH, INC. (US) 1989-05-30 US disclosed
EP-0223588-A1 Process for the preparation of beta-lactam compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-05-27 EP disclosed
EP-0028892-B1 A HETERONUCLEAR-BRIDGED RHODIUM CLUSTER AND ITS APPLICATION AS CATALYST FOR HYDROFORMYLATION OF OLEFINS UNION CARBIDE CORPORATION (US) 1986-03-19 EP disclosed