Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160186 | 1.00 | NPC1 (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18160143 | 0.97 | MAPT (0.52) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18157755 | 0.91 | NPC1 (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL28555372 | 0.91 | NPC1 (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18160288 | 0.90 | KIF11 (0.45) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18157734 | 0.90 | MAPT (0.47) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18157750 | 0.90 | NFE2L2 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18160287 | 0.90 | NFE2L2 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18157738 | 0.90 | MAPT (0.47) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL18157754 | 0.88 | RELA (0.55) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | NPC1 1892/4885RAB9A 679/4885MAPT 2538/4885 |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | NPC1 1892/4885RAB9A 679/4885MAPT 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.