SCHEMBL18157733

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18160289	1.00	NFE2L2 (0.55)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18160168	0.97	ALDH1A1 (0.51)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL28555372	0.91	NPC1 (0.50)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18157755	0.91	NPC1 (0.50)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18160185	0.90	NFE2L2 (0.58)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18180636	0.90	MAPT (0.46)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18180638	0.90	MAPT (0.46)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18157750	0.90	NFE2L2 (0.53)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18180637	0.90	MAPT (0.46)	NFE2L2KMT2AMEN1MAPTALDH1A1
	SCHEMBL18160287	0.90	NFE2L2 (0.53)	NFE2L2KMT2AMEN1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.