Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.84 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690031 | 0.91 | HSD11B1 (1.00) | HSD11B1RECQLKAT6AKMT2AMEN1 | |
| SCHEMBL10202538 | 0.85 | HSD11B1 (0.65) | HSD11B1KAT6AALDH1A1POLBKEAP1 | |
| SCHEMBL6203408 | 0.84 | HSD11B1 (1.00) | HSD11B1RECQLKMT2AMEN1NPC1 | |
| SCHEMBL6904124 | 0.84 | HSD11B1 (0.88) | HSD11B1RECQLKMT2AMEN1NPC1 | |
| SCHEMBL28392128 | 0.81 | HSD11B1 (0.69) | HSD11B1RECQLKAT6AKMT2AMEN1 | |
| SCHEMBL15741700 | 0.81 | HSD11B1 (0.59) | HSD11B1NPC1ALDH1A1POLBKEAP1 | |
| SCHEMBL2069738 | 0.81 | HSD11B1 (0.59) | HSD11B1KAT6AALDH1A1POLBHDAC3 | |
| SCHEMBL30209485 | 0.81 | HSD11B1 (0.80) | HSD11B1RECQLKMT2AMEN1NPC1 | |
| SCHEMBL452973 | 0.79 | HSD11B1 (0.77) | HSD11B1RECQLKMT2AMEN1NPC1 | |
| SCHEMBL29609513 | 0.78 | HSD11B1 (0.74) | HSD11B1RECQLKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-A | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2020-11-24 | — | — | CN | disclosed |