Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.88 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203408 | 0.94 | HSD11B1 (1.00) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| SCHEMBL28497899 | 0.86 | HSD11B1 (0.76) | HSD11B1RECQLMEN1KMT2AHTT | |
| SCHEMBL29690031 | 0.84 | HSD11B1 (1.00) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| SCHEMBL28555693 | 0.84 | HSD11B1 (0.84) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| SCHEMBL452973 | 0.83 | HSD11B1 (0.77) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| SCHEMBL2422002 | 0.82 | RECQL (1.00) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| SCHEMBL4592282 | 0.82 | HTT (0.70) | HSD11B1MEN1KMT2AHTTNPSR1 | |
| SCHEMBL29609513 | 0.81 | HSD11B1 (0.74) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| SCHEMBL12259460 | 0.81 | HSD11B1 (0.63) | HSD11B1RECQLMEN1KMT2AHTT | |
| SCHEMBL29609963 | 0.81 | RECQL (0.97) | HSD11B1RECQLMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-110981676-B | Method for preparing beta-ketosulfone compound through visible light mediated atoxic acid decarboxylation ketonization reaction | 西南大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-111978216-A | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-110981676-A | Method for preparing β -ketosulfone compound through visible light mediated atoxic acid decarboxylation ketonization reaction | 西南大学 | 2020-04-10 | — | — | CN | disclosed |
| US-6767926-B1 | Method for protecting normal cells from cytotoxicity of chemotherapeutic agents | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2004-07-27 | — | — | US | disclosed |