SCHEMBL28556166

SCHEMBL28556166

CCO[Si](CCCCOC(=O)CC)(OCC)OCC

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.55
HTT P42858 1/20 0.41
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
FAAH O00519 1/20 0.35
ACHE P22303 6/20 0.34
HTR2C P28335 1/20 0.34
DGKA P23743 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30226988 0.98 NAAA (0.58) NAAAHTTRAD52NPSR1FAAH
SCHEMBL1224968 0.94 NAAA (0.52) NAAAHTTRAD52NPSR1FAAH
SCHEMBL28289669 0.87 HTR2C (0.47) NAAARAD52NPSR1FAAHACHE
SCHEMBL29028494 0.87 HTR2C (0.47) NAAARAD52NPSR1FAAHACHE
SCHEMBL15356546 0.86 NAAA (0.45) NAAAHTTDGKAGAAALDH1A1
SCHEMBL28379557 0.86 NAAA (0.47) NAAAHTTRAD52NPSR1FAAH
SCHEMBL17599123 0.85 NAAA (0.45) NAAAHTTRAD52NPSR1FAAH
SCHEMBL27982320 0.85 NAAA (0.56) NAAAHTTRAD52NPSR1FAAH
SCHEMBL5574981 0.84 TRPA1 (0.47) NAAAHTTRAD52NPSR1FAAH
SCHEMBL9323713 0.83 GAA (0.46) NAAAFAAHACHEDGKAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428785-B Silanes and curable compositions containing silanes as crosslinkers 汉高股份有限及两合公司 2021-05-07 CN disclosed