Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15546329 | 1.00 | NR4A1 (0.34) | NR4A1NR4A2NR4A3KDM4ETSHR | |
| SCHEMBL28062185 | 0.79 | KDM4E (0.33) | NR4A1NR4A2NR4A3KDM4ETSHR | |
| Hydrogen Peroxide SCHEMBL28392769 | 0.79 | TSHR (0.33) | KDM4ETSHR | |
| SCHEMBL5892077 | 0.79 | KDM4E (0.33) | NR4A1NR4A2NR4A3KDM4ETSHR | |
| SCHEMBL3630555 | 0.79 | TSHR (0.33) | KDM4ETSHR | |
| SCHEMBL1965963 | 0.79 | TSHR (0.33) | KDM4ETSHR | |
| SCHEMBL1965967 | 0.79 | TSHR (0.33) | KDM4ETSHR | |
| SCHEMBL2855633 | 0.77 | TSHR (0.36) | KDM4ETSHR | |
| SCHEMBL1415787 | 0.77 | TSHR (0.43) | KDM4ETSHR | |
| SCHEMBL2855707 | 0.77 | TSHR (0.36) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150196585-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | VIFOR (INTERNATIONAL) LTD. (CH) | 2015-07-16 | — | — | US | disclosed |
| US-20150183908-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | VIFOR (INTERNATIONAL) LTD. (CH) | 2015-07-02 | — | — | US | disclosed |
| EP-2874633-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | Relypsa, Inc. (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014015244-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | SORBENT THERAPEUTICS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |
| WO-2014015240-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | SORBENT THERAPEUTICS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183908-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | PICALM, ORAI1, KCNN3 | NR4A1 3744/4885NR4A2 4445/4885NR4A3 4101/4885 |
| US-20150196585-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | SSB, PARG, HLA-DRB1 | NR4A1 3855/4885NR4A2 4308/4885NR4A3 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.