Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288511 | 0.86 | RAB9A (0.68) | NPC1KMT2ARAB9AL3MBTL1NPSR1 | |
| SCHEMBL3050543 | 0.86 | EPHX1 (0.69) | NPC1KMT2ARAB9AL3MBTL1NPSR1 | |
| SCHEMBL28329528 | 0.85 | ALDH1A1 (0.52) | NPC1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL2347310 | 0.85 | RAB9A (0.77) | NPC1KMT2ARAB9AL3MBTL1NPSR1 | |
| SCHEMBL28914436 | 0.84 | L3MBTL1 (0.49) | NPC1KMT2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL11515049 | 0.84 | PLK1 (0.65) | NPC1KMT2ARAB9ANPSR1EPHX1 | |
| SCHEMBL2343610 | 0.84 | NPC1 (0.74) | NPC1KMT2ARAB9AL3MBTL1NPSR1 | |
| SCHEMBL29661214 | 0.84 | ALDH1A1 (0.70) | NPC1KMT2ARAB9AL3MBTL1NPSR1 | |
| SCHEMBL29661130 | 0.84 | NPC1 (0.74) | NPC1KMT2ARAB9AL3MBTL1NPSR1 | |
| SCHEMBL2343630 | 0.84 | ALDH1A1 (0.70) | NPC1KMT2ARAB9AL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112807294-B | Application of acyl thiourea compound in preparation of medicines for treating or preventing herpes simplex virus type I infection | 武汉大学 | 2023-09-05 | — | — | CN | claimed |
| CN-113582969-A | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2021-11-02 | — | — | CN | claimed |
| CN-112807294-A | Application of acylthiourea compound in preparation of medicine for treating or preventing herpes simplex virus I-type infection | 武汉大学 | 2021-05-18 | — | — | CN | claimed |
| CN-112807294-B | Application of acyl thiourea compound in preparation of medicines for treating or preventing herpes simplex virus type I infection | 武汉大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-113582969-B | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-113582969-A | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-112807294-A | Application of acylthiourea compound in preparation of medicine for treating or preventing herpes simplex virus I-type infection | 武汉大学 | 2021-05-18 | — | — | CN | disclosed |