Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL3210007 | 0.83 | CYP3A4 (0.36) | AKR1C3ALDH1A1TSHRMEN1KMT2A | |
| Styrene SCHEMBL28015835 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1 | |
| Styrene SCHEMBL1628243 | 0.78 | AKR1C3 (0.81) | AKR1C3APEX1ALDH1A1TSHRHTT | |
| Styrene SCHEMBL10920265 | 0.78 | AKR1C3 (0.44) | AKR1C3APEX1ALDH1A1TSHRHTT | |
| Styrene SCHEMBL2853955 | 0.77 | HCAR2 (0.47) | ALDH1A1TSHRGLATDP1PKM | |
| Styrene SCHEMBL28079565 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL10764443 | 0.76 | AKR1C3 (0.44) | AKR1C3APEX1ALDH1A1HTTGLA | |
| Styrene SCHEMBL7177772 | 0.75 | AKR1C3 (0.46) | AKR1C3APEX1ALDH1A1TSHRHTT | |
| Styrene SCHEMBL531225 | 0.75 | AKR1C3 (0.46) | AKR1C3APEX1ALDH1A1TSHRHTT | |
| Methacrylic Acid SCHEMBL8608400 | 0.74 | GLA (0.41) | AKR1C3ALDH1A1GLATDP1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190022-B1 | LUBRICATING OIL ADDITIVES | LUBRIZOL CORP (US) | 2004-12-29 | — | — | EP | claimed |
| EP-1190021-B1 | LUBRICATING OIL ADDITIVES | LUBRIZOL CORP (US) | 2004-12-01 | — | — | EP | claimed |
| EP-2199333-B1 | Binder-strengthened textile sheet, method for its production and application | JOHNS MANVILLE EUROPE GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2199333-A1 | Binder-strengthened textile sheet, method for its production and application | Johns Manville Europe GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |