Styrene

Styrene

SCHEMBL3210007

C=Cc1ccccc1.CCC(=CC1=CC(=O)OC1=O)C(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
TBXAS1 P24557 2/20 0.35
EPHX2 P34913 2/20 0.34
PPARG P37231 1/20 0.33
AKR1C3 P42330 1/20 0.33
RECQL P46063 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.31
PTGS2 P35354 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2855732 0.83 AKR1C3 (0.50) ALDH1A1TSHRAKR1C3MEN1KMT2A
Styrene SCHEMBL28015835 0.77 ALDH1A1 (0.52) ALDH1A1TSHRTDP1
Styrene SCHEMBL28040202 0.76 ALDH1A1 (0.50) CYP3A4CYP2C9ALDH1A1TSHRTBXAS1
Styrene SCHEMBL2853955 0.74 HCAR2 (0.47) CYP2C9ALDH1A1TSHRRECQLLMNA
Styrene SCHEMBL28079565 0.73 ALDH1A1 (0.47) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL309762 0.72 CYP3A4 (0.63) CYP3A4CYP2C9ALDH1A1TSHRTBXAS1
SCHEMBL57683 0.72 CYP3A4 (0.63) CYP3A4CYP2C9ALDH1A1TSHRTBXAS1
SCHEMBL2918640 0.72 CYP3A4 (0.63) CYP3A4CYP2C9ALDH1A1TSHRTBXAS1
Styrene SCHEMBL27534959 0.71 ALDH1A1 (0.44) ALDH1A1TSHRMEN1KMT2ALMNA
Styrene SCHEMBL7177777 0.70 ALDH1A1 (0.40) CYP3A4CYP2C9ALDH1A1TSHRAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100062669-A1 MULTI-COMPONENT FIBERS CONTAINING HIGH CHAIN-LENGTH POLYAMIDES ARKEMA INC. (US) 2010-03-11 US disclosed