Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28623066 | 0.91 | TP53 (0.38) | TP53CA5ACA5BALDH1A1BLM | |
| SCHEMBL27489947 | 0.90 | ALDH1A1 (0.37) | TP53CA5ACA5BALDH1A1BLM | |
| Sulfuric Acid SCHEMBL28238705 | 0.84 | TP53 (0.41) | TP53CA5ACA5BALDH1A1BLM | |
| Sulfuric Acid SCHEMBL11155340 | 0.84 | ALDH1A1 (0.62) | TP53CA5ACA5BALDH1A1BLM | |
| Sulfuric Acid SCHEMBL2127327 | 0.84 | TP53 (0.41) | TP53CA5ACA5BALDH1A1BLM | |
| Sulfuric Acid SCHEMBL11327555 | 0.84 | ALDH1A1 (0.62) | TP53CA5ACA5BALDH1A1BLM | |
| SCHEMBL28621094 | 0.83 | GABBR2 (0.38) | TP53ALDH1A1BLMCYP2C19LMNA | |
| Sulfuric Acid SCHEMBL8088341 | 0.81 | TP53 (0.39) | TP53CA5ACA5BALDH1A1BLM | |
| Sulfuric Acid SCHEMBL10863257 | 0.81 | ALDH1A1 (0.59) | TP53CA5ACA5BALDH1A1BLM | |
| Methyl Alcohol SCHEMBL27870275 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112852695-B | Recombinant escherichia coli for producing isobutylamine as well as construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2021-12-03 | — | — | CN | disclosed |
| CN-112852695-A | Recombinant escherichia coli for producing isobutylamine as well as construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | disclosed |