Butane

Butane

SCHEMBL2855752

CCCC.O=C(O)CCC(=O)OC1CC1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.53
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
FFAR3 O14843 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
KDM6B O15054 1/20 0.41
KDM5C P41229 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
PHF8 Q9UPP1 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
ALDH1A1 P00352 1/20 0.38
MMP3 P08254 1/20 0.37
AKR1B1 P15121 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19690549 0.92 LMNA (0.47) NAAALMNAGAAMAPTKDM6B
SCHEMBL5071456 0.92 LMNA (0.47) NAAALMNAGAAMAPTKDM6B
Butane SCHEMBL2857848 0.91 NAAA (0.65) NAAALMNAKDM6BKDM5CEGLN1
SCHEMBL8257993 0.84 LMNA (0.42) NAAALMNAGAAMAPTKDM6B
SCHEMBL2818269 0.84 LMNA (0.42) NAAALMNAGAAMAPTKDM6B
SCHEMBL27617118 0.83 NAAA (0.52) NAAALMNAGAAMAPTKDM6B
SCHEMBL3473161 0.83 NAAA (0.56) NAAALMNAKDM6BKDM5CEGLN1
SCHEMBL8690677 0.83
SCHEMBL19690548 0.82 NAAA (0.52) NAAAGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL6864567 0.82 LMNA (0.41) NAAALMNAGAAMAPTKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP disclosed
CN-112204055-B Polypropylene composition and molded article 巴塞尔聚烯烃意大利有限公司 2022-01-18 CN disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
CN-112789296-A Polypropylene composition and molded article 巴塞尔聚烯烃意大利有限公司 2021-05-11 CN disclosed
CN-107915794-B Catalyst component for olefin polymerization and application thereof, catalyst for olefin polymerization and application thereof, and olefin polymerization method 中国石油化工股份有限公司 2021-03-16 CN disclosed
WO-2021015191-A1 EXPANDABLE POLYPROPYLENE COMPOSITION AND INJECTION MOLDED FOAM サンアロマー株式会社 2021-01-28 WO disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
CN-110036068-A Concentrate composition 巴塞尔聚烯烃意大利有限公司 2019-07-19 CN disclosed
CN-109923170-A Concentrate composition and polypropylene resin composite comprising the concentrate composition 胜亚诺盟股份有限公司 2019-06-21 CN disclosed
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2697271-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-02-19 EP disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
CN-101842396-B Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization method MITSUI CHEMICALS INC 2013-03-20 CN disclosed
WO-2012139897-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-10-18 WO disclosed
CN-101842396-A Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization method MITSUI CHEMICALS INC 2010-09-22 CN disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed
CN-1285623-C Catalyst system for olefin polymerization BASELL POLIOLEFINE SPA (IT) 2006-11-22 CN disclosed
CN-1545525-A Catalyst system for olefin polymerization ��������ϩ����������޹�˾ 2004-11-10 CN disclosed