Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856275 | 0.93 | ALDH1A1 (0.52) | MEN1KMT2AKCNQ2LMNAMAPT | |
| SCHEMBL2856274 | 0.85 | MAPT (0.49) | LMNAMAPTPKMALDH1A1MAPK1 | |
| SCHEMBL2861253 | 0.84 | MAPT (0.53) | LMNAMAPTPKMALDH1A1HPGD | |
| SCHEMBL2854758 | 0.83 | MEN1 (0.49) | MEN1KMT2AKCNQ2LMNAMAPT | |
| SCHEMBL2856509 | 0.82 | MAPT (0.48) | LMNAMAPTPKMALDH1A1KDM4E | |
| SCHEMBL2853248 | 0.81 | MAPT (0.48) | MEN1KMT2ALMNAMAPTPKM | |
| SCHEMBL2854695 | 0.81 | MAPT (0.50) | LMNAMAPTPKMALDH1A1POLB | |
| SCHEMBL2852672 | 0.81 | MAPT (0.60) | KMT2ALMNAMAPTPKMALDH1A1 | |
| SCHEMBL2860824 | 0.80 | LMNA (0.57) | MEN1KMT2ALMNAMAPTPKM | |
| SCHEMBL2853491 | 0.80 | ALDH1A1 (0.55) | LMNAMAPTPKMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |