SCHEMBL2855825

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3743698	0.81	AOC3 (0.53)	CES2CES1AOC3KDM4ETSHR
	SCHEMBL229877	0.75	CES2 (0.45)	CES2CES1IGFBP3BRD4HDAC4
	SCHEMBL20862602	0.73	CES2 (0.46)	CES2CES1IGFBP3BRD4HDAC4
	SCHEMBL14415719	0.73	SLC6A2 (0.44)	CES2CES1AOC3KDM4EBRD4
	SCHEMBL2861781	0.72	CES2 (0.38)	CES2CES1IGFBP3BRD4HDAC4
	SCHEMBL227352	0.72	CES2 (0.55)	CES2CES1IGFBP3BRD4HDAC4
	SCHEMBL5512985	0.72	LMNA (0.44)	CES2CES1AOC3BRD4CREBBP
	SCHEMBL6204070	0.71	AOC3 (0.50)	CES2CES1AOC3KDM4EHDAC4
	SCHEMBL14415756	0.71	CES2 (0.41)	CES2CES1IGFBP3BRD4CREBBP
	SCHEMBL18623176	0.71	CES2 (0.41)	CES2CES1IGFBP3IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.