Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17871848 | 0.87 | KMT2A (0.41) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL3220834 | 0.81 | ALDH1A1 (0.50) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL23064633 | 0.81 | MEN1 (0.48) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL27978816 | 0.80 | ALDH1A1 (0.47) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL31376167 | 0.80 | ADRA2C (0.55) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL414216 | 0.80 | ADRA2C (0.55) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL28452171 | 0.79 | KEAP1 (0.52) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL31167266 | 0.79 | KEAP1 (0.52) | KMT2ALMNAMEN1THRBBLM | |
| SCHEMBL1982675 | 0.79 | KEAP1 (0.52) | KMT2ALMNAMEN1THRBBLM | |
| Hydrochloric Acid SCHEMBL5154521 | 0.79 | ADRA2C (0.53) | KMT2ALMNAMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108654695-B | Indole [3,2-a ] oxazolidine-labeled ruthenium carbene catalyst, and preparation method and application thereof | 天津大学 | 2021-04-06 | — | — | CN | disclosed |