Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20415684 | 1.00 | ITGB3 (0.46) | ITGB3ITGA2BPPARGPPARACTSS | |
| SCHEMBL18262422 | 0.89 | LDHA (0.39) | ITGB3ITGA2BCTSLALDH1A1 | |
| SCHEMBL18262421 | 0.89 | LDHA (0.39) | ITGB3ITGA2BCTSLALDH1A1 | |
| SCHEMBL28562309 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BPPARGPPARACTSS | |
| SCHEMBL28558404 | 0.80 | ALDH1A1 (0.36) | PPARGPPARAALDH1A1LMNA | |
| SCHEMBL18262546 | 0.79 | LDHA (0.36) | ITGB3ITGA2BCTSLALDH1A1 | |
| SCHEMBL18262544 | 0.79 | LDHA (0.36) | ITGB3ITGA2BCTSLALDH1A1 | |
| SCHEMBL18262541 | 0.79 | LDHA (0.36) | ITGB3ITGA2BCTSLALDH1A1 | |
| SCHEMBL22723020 | 0.79 | LDHA (0.37) | PPARGPPARAALDH1A1 | |
| SCHEMBL22723021 | 0.79 | LDHA (0.37) | PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |