Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912380 | 0.85 | TSHR (0.52) | ALOX15HTTKDM4EALDH1A1HPGD | |
| SCHEMBL31345639 | 0.85 | ALOX15 (0.49) | ALOX15HTTKDM4EALDH1A1HPGD | |
| SCHEMBL3307271 | 0.85 | ALOX15 (0.49) | ALOX15HTTKDM4EALDH1A1HPGD | |
| SCHEMBL15128363 | 0.84 | ALOX15 (0.48) | ALOX15HTTKDM4EALDH1A1HPGD | |
| SCHEMBL253152 | 0.84 | KDM4E (0.48) | ALOX15HTTKDM4EALDH1A1HPGD | |
| SCHEMBL3458121 | 0.83 | SMN1; SMN2 (0.53) | HTTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL125290 | 0.83 | LMNA (0.51) | ALOX15KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL10233174 | 0.82 | ALDH1A1 (0.49) | ALOX15KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL5897292 | 0.81 | LMNA (0.42) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5200908 | 0.81 | PARP1 (0.50) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778306-B | Synthesis method of 1, 8-naphthyridine derivative | 吉林化工学院 | 2024-01-26 | — | — | CN | disclosed |
| CN-112778306-A | Synthetic method of 1, 8-naphthyridine derivative | 吉林化工学院 | 2021-05-11 | — | — | CN | disclosed |