SCHEMBL2855928

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2854954	0.89	MAPK14 (0.60)	MAPK14BRAFMETMAPK13KDR
	SCHEMBL1136971	0.88	MAPK14 (0.65)	MAPK14BRAFMETMAPK13KDR
	SCHEMBL2860620	0.86	RAF1 (0.50)	MAPK14BRAFMAPK13KDRRIPK2
	SCHEMBL3561767	0.85	MAPK14 (0.61)	MAPK14BRAFMETMAPK13KDR
	SCHEMBL2858354	0.81	MAPK14 (0.63)	MAPK14BRAFMETMAPK13KDR
	SCHEMBL12812041	0.81	MAPK14 (0.51)	MAPK14BRAFMETKDRRAF1
	SCHEMBL4321614	0.77	MET (0.72)	MAPK14BRAFMETRAF1
	SCHEMBL23201734	0.77	MAPK14 (1.00)	MAPK14BRAFMAPK13KDRRIPK2
	SCHEMBL29844389	0.77	MAPK14 (1.00)	MAPK14BRAFMAPK13KDRRIPK2
	SCHEMBL13635346	0.77	MAPK14 (0.52)	MAPK14BRAFMETKDRRIPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.