Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.47 |
| ▸ | THRA | P10827 | 14/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566363 | 0.84 | PTGDR2 (0.42) | THRBMAPK14PTGDR2PTGER1P2RX3 | |
| SCHEMBL21749540 | 0.83 | THRB (0.51) | THRBTHRA | |
| SCHEMBL21749364 | 0.81 | THRB (0.43) | THRBTHRA | |
| SCHEMBL28913436 | 0.81 | THRB (0.62) | THRBTHRAMAPK14 | |
| SCHEMBL28560603 | 0.81 | THRB (0.64) | THRBTHRA | |
| SCHEMBL28561278 | 0.80 | THRB (0.42) | THRBTHRAMAPK14 | |
| SCHEMBL21749494 | 0.77 | THRB (0.73) | THRBTHRA | |
| SCHEMBL21769842 | 0.77 | THRA (0.49) | THRBTHRA | |
| SCHEMBL13116448 | 0.76 | THRB (0.55) | THRBTHRA | |
| SCHEMBL21749557 | 0.76 | THRA (0.58) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805005-A | Thyroxine receptor beta agonist compounds | 拓臻股份有限公司 | 2021-05-14 | — | — | CN | disclosed |