Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749467 | 0.86 | NPBWR1 (0.38) | PTGDR2NPBWR1CACNA1HP2RX3THRB | |
| SCHEMBL21749429 | 0.84 | NPBWR1 (0.36) | PTGDR2NPBWR1CACNA1HP2RX3THRB | |
| SCHEMBL28559669 | 0.84 | THRB (0.47) | PTGDR2P2RX3MAPK14PTGER1THRB | |
| SCHEMBL21749380 | 0.80 | NPBWR1 (0.47) | NPBWR1THRB | |
| SCHEMBL21749514 | 0.80 | NPBWR1 (0.42) | NPBWR1THRBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28566985 | 0.80 | NPBWR1 (0.43) | PTGDR2NPBWR1THRB | |
| SCHEMBL21769493 | 0.80 | NPBWR1 (0.36) | MKNK2NPBWR1CACNA1HTHRBSLC16A3 | |
| SCHEMBL28561074 | 0.79 | NPBWR1 (0.47) | NPBWR1THRBMAPT | |
| SCHEMBL21769494 | 0.78 | NPBWR1 (0.35) | MKNK2NPBWR1CACNA1HTHRBSLC16A3 | |
| SCHEMBL21769495 | 0.76 | THRB (0.36) | NPBWR1THRBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805005-A | Thyroxine receptor beta agonist compounds | 拓臻股份有限公司 | 2021-05-14 | — | — | CN | disclosed |