SCHEMBL28560110

SCHEMBL28560110

C[Na].Cc1cnc2ccccc2n1.O[Si](O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
ALDH1A1 P00352 4/20 0.44
HPGD P15428 2/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PDE10A Q9Y233 1/20 0.44
KDM4E B2RXH2 3/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 2/20 0.42
MAPT P10636 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPK10 P53779 1/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 1/20 0.42
HTR3A P46098 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28571 0.89 PDE10A (0.52) CYP1A2ALDH1A1HPGDALOX15HSD17B10
Water SCHEMBL16742371 0.87 PDE10A (0.50) CYP1A2ALDH1A1HPGDALOX15HSD17B10
Hydrochloric Acid SCHEMBL29004253 0.87 PDE10A (0.50) CYP1A2ALDH1A1HPGDALOX15HSD17B10
SCHEMBL30961661 0.87 PDE10A (0.50) CYP1A2ALDH1A1HPGDALOX15HSD17B10
Ethane SCHEMBL11413846 0.87 PDE10A (0.50) CYP1A2ALDH1A1HPGDALOX15HSD17B10
Formaldehyde SCHEMBL28095446 0.83 ALDH1A1 (0.47) CYP1A2ALDH1A1HPGDALOX15HSD17B10
SCHEMBL8174635 0.81 ALDH1A1 (0.55) CYP1A2ALDH1A1HPGDALOX15HSD17B10
SCHEMBL8174637 0.81 ALDH1A1 (0.46) CYP1A2ALDH1A1HPGDALOX15HSD17B10
Acetaldehyde SCHEMBL11425484 0.80 ALDH1A1 (0.44) CYP1A2ALDH1A1HPGDALOX15HSD17B10
SCHEMBL28242358 0.80 NCF1 (0.48) CYP1A2ALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113615696-A Pyridine amide compounds having fungicidal activity 美国陶氏益农公司 2021-11-09 CN disclosed
CN-107205405-B Pyridine amide compounds having fungicidal activity 美国陶氏益农公司 2021-08-24 CN disclosed
CN-113173838-A Pyridine amide compounds having fungicidal activity 美国陶氏益农公司 2021-07-27 CN disclosed
CN-107205386-B Pyridinamides with fungicidal activity 美国陶氏益农公司 2021-07-23 CN disclosed
CN-107207414-B Pyridine amide compounds having fungicidal activity 美国陶氏益农公司 2021-03-30 CN disclosed