SCHEMBL28571

SCHEMBL28571

Cc1cnc2ccccc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.52
CYP1A2 P05177 3/20 0.50
NPC1 O15118 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
HTT P42858 3/20 0.48
RAB9A P51151 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ATM Q13315 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HTR3A P46098 1/20 0.48
HRH4 Q9H3N8 1/20 0.48
KDM4E B2RXH2 2/20 0.48
GPR3 P46089 1/20 0.48
MAPT P10636 1/20 0.48
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
NQO2 P16083 1/20 0.46
CCNB2 O95067 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29004253 0.98 PDE10A (0.50) PDE10ACYP1A2NPC1ALDH1A1HPGD
Ethane SCHEMBL11413846 0.98 PDE10A (0.50) PDE10ACYP1A2NPC1ALDH1A1HPGD
SCHEMBL30961661 0.98 PDE10A (0.50) PDE10ACYP1A2NPC1ALDH1A1HPGD
Water SCHEMBL16742371 0.98 PDE10A (0.50) PDE10ACYP1A2NPC1ALDH1A1HPGD
Formaldehyde SCHEMBL28095446 0.93 ALDH1A1 (0.47) PDE10ACYP1A2NPC1ALDH1A1HPGD
SCHEMBL28560110 0.89 CYP1A2 (0.47) PDE10ACYP1A2NPC1ALDH1A1HPGD
SCHEMBL28242358 0.89 NCF1 (0.48) PDE10ACYP1A2NPC1ALDH1A1HPGD
Acetaldehyde SCHEMBL11425484 0.89 ALDH1A1 (0.44) PDE10ACYP1A2NPC1ALDH1A1HPGD
SCHEMBL19508472 0.87 NQO2 (0.56) PDE10ACYP1A2NPC1ALDH1A1RAB9A
Decane SCHEMBL11419386 0.86 KDM4E (0.50) PDE10ACYP1A2NPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3193 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709714-A1 SUBSTITUTED QUINOXALINES Mirati Therapeutics, Inc. (US) 2026-03-18 EP claimed
WO-2024238221-A1 SUBSTITUTED QUINOXALINES Mirati Therapeutics, Inc. (US) 2024-11-21 WO claimed
CN-117945995-A Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof 中国科学院青海盐湖研究所 2024-04-30 CN claimed
CN-117658931-A Washing-free targeting lipid drop probe and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-03-08 CN claimed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US claimed
US-20230132298-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, LLC 2023-04-27 US claimed
US-11578087-B2 Oxaborole esters and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2023-02-14 US claimed
CN-114805225-B Hydrogenation method of methyl quinoxaline 苏州中车氢能动力技术有限公司 2022-09-23 CN claimed
CN-110218195-B Stable isotope labeled quinoxaline-2-carboxylic acid and synthesis method thereof 上海安谱实验科技股份有限公司 2022-08-09 CN claimed
CN-114805225-A Hydrogenation method of methyl quinoxaline 苏州中车氢能动力技术有限公司 2022-07-29 CN claimed
US-6361979-B1 OXIDATION USING MICROORGANISM PFIZER INC. 2002-03-26 US claimed
EP-1106700-A2 Microbial cleavage of organic c-n bonds Petroleo Brasileiro S.A. - PETROBAS (BR) 2001-06-13 EP claimed
CN-1273276-A Microbiological inversion of 2-methyl-quinoxaline PFIZER PRODUCT CORP (US) 2000-11-15 CN claimed
EP-1028164-A1 Microbial conversion of 2-methylquinoxaline Pfizer Products Inc. (US) 2000-08-16 EP claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
US-4228151-A QUINOXALINE DIOXIDE L'OREAL (FR) 1980-10-14 US claimed
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US claimed