Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14206623 | 0.88 | ALDH1A1 (0.34) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL23977005 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL24781339 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL17550157 | 0.74 | SRD5A1 (0.42) | HTR6 | |
| SCHEMBL17542389 | 0.74 | SRD5A1 (0.42) | HTR6 | |
| SCHEMBL17542142 | 0.74 | SRD5A1 (0.42) | HTR6 | |
| SCHEMBL24542989 | 0.71 | HTR2C (0.41) | — | |
| SCHEMBL29673081 | 0.71 | HTR2C (0.41) | — | |
| SCHEMBL27473920 | 0.71 | ESR1 (0.51) | HTR6 | |
| SCHEMBL27486916 | 0.70 | CYP17A1 (0.41) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121497-A | Substituted tetrahydroquinolinone compounds as ROR gamma modulators | 奥瑞基尼探索技术有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-108026045-B | Substituted tetrahydroquinolinone compounds as ROR gamma modulators | 奥瑞基尼探索技术有限公司 | 2021-04-27 | — | — | CN | disclosed |