Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173938 | 1.00 | MEN1 (0.73) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL28548697 | 0.86 | MEN1 (0.82) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL28555356 | 0.86 | MEN1 (0.77) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL3456311 | 0.85 | MEN1 (1.00) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL3456310 | 0.85 | MEN1 (1.00) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL28358299 | 0.84 | MEN1 (0.74) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL28361850 | 0.84 | MEN1 (0.74) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL28358398 | 0.84 | MEN1 (0.74) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL11264716 | 0.84 | PTGS2 (0.69) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL28358178 | 0.83 | MEN1 (0.73) | MEN1KMT2AKDM4ENPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679470-B | (E) -1-phenyl-4-alkenyl-1H-pyrazole compound and medical application thereof | 中国药科大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-112679470-A | (E) -1-phenyl-4-alkenyl-1H-pyrazole compound and medical application thereof | 中国药科大学 | 2021-04-20 | — | — | CN | disclosed |