Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577953 | 0.76 | KDM4E (0.41) | ADORA3ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL28033963 | 0.74 | ALDH1A1 (0.50) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL30443451 | 0.73 | KDM4E (0.50) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL30443261 | 0.73 | ILK (0.42) | ADORA3ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL22463747 | 0.73 | ADORA2A (0.56) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL28561492 | 0.73 | KDM4E (0.50) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL28577760 | 0.72 | ADORA2A (0.45) | ADORA3ADORA2AADORA1ADORA2BRAB9A | |
| SCHEMBL30443202 | 0.72 | ADORA2A (0.45) | ADORA3ADORA2AADORA1ADORA2BRAB9A | |
| SCHEMBL28561330 | 0.71 | APP (0.40) | ADORA3ADORA2AALDH1A1KDM4EMAPT | |
| SCHEMBL28914012 | 0.71 | APP (0.40) | CYP19A1KDM4EMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |