Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28561330 | 0.84 | APP (0.40) | APPLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL28577953 | 0.84 | KDM4E (0.41) | APPLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL30443461 | 0.74 | IDO1 (0.39) | SMN1; SMN2RAB9AKDM4ECYP19A1 | |
| SCHEMBL29439805 | 0.74 | RAB9A (0.35) | APPLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL22715224 | 0.74 | RAB9A (0.35) | APPLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL30443202 | 0.73 | ADORA2A (0.45) | RAB9A | |
| SCHEMBL28577760 | 0.73 | ADORA2A (0.45) | RAB9A | |
| SCHEMBL30443261 | 0.71 | ILK (0.42) | LMNASMN1; SMN2RAB9AKDM4EMAPT | |
| SCHEMBL28560913 | 0.71 | ADORA3 (0.46) | LMNARAB9AKDM4EMAPTMEN1 | |
| SCHEMBL30443451 | 0.71 | KDM4E (0.50) | SMN1; SMN2RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |