Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 6/20 | 0.50 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856027 | 0.82 | BCHE (0.79) | BCHECYP2D6LMNAHTTKDM4E | |
| SCHEMBL24216492 | 0.79 | HRH3 (0.51) | BCHECYP2D6LMNAHTTKDM4E | |
| SCHEMBL30409802 | 0.79 | HRH3 (0.51) | BCHECYP2D6LMNAHTTKDM4E | |
| SCHEMBL26912467 | 0.76 | MAPT (0.53) | CYP2D6LMNAKDM4EDRD2DRD4 | |
| SCHEMBL31217232 | 0.73 | EGFR (0.56) | BCHECYP2D6LMNAHTTKDM4E | |
| SCHEMBL19252887 | 0.73 | HRH3 (0.54) | BCHECYP2D6LMNAHTTKDM4E | |
| SCHEMBL29479428 | 0.73 | DRD4 (0.58) | BCHECYP2D6MAPK1DRD2DRD4 | |
| SCHEMBL13050952 | 0.73 | HRH3 (0.56) | BCHECYP2D6LMNAHTTKDM4E | |
| SCHEMBL27868474 | 0.73 | HRH3 (0.54) | BCHECYP2D6LMNAHTTKDM4E | |
| SCHEMBL7667948 | 0.73 | BCHE (0.66) | BCHECYP2D6LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848964-B | EBNA1 inhibitors and methods of using the same | 威斯塔解剖学和生物学研究所 | 2021-03-19 | — | — | CN | disclosed |