Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611143 | 0.78 | ELANE (0.46) | MAPTKDM4ETHRBALDH1A1PDGFRB | |
| SCHEMBL24331569 | 0.78 | ELANE (0.46) | MAPTKDM4ETHRBALDH1A1PDGFRB | |
| SCHEMBL14837630 | 0.76 | IMPDH2 (0.58) | MAPTKDM4EALDH1A1LMNAIMPDH2 | |
| SCHEMBL26912673 | 0.76 | MAPT (0.59) | MAPTKDM4ETHRBALDH1A1PDGFRB | |
| SCHEMBL28561190 | 0.76 | BCHE (0.54) | KDM4ELMNAL3MBTL1DRD2DRD4 | |
| SCHEMBL1413396 | 0.72 | ALDH1A1 (0.55) | MAPTKDM4ETHRBALDH1A1PDGFRB | |
| SCHEMBL26912090 | 0.72 | CYP2D6 (0.65) | MAPTKDM4ETHRBALDH1A1CYP2D6 | |
| SCHEMBL26911773 | 0.69 | CYP2D6 (0.68) | MAPTKDM4ETHRBALDH1A1CYP2D6 | |
| SCHEMBL26911783 | 0.68 | HTR1A (0.60) | MAPTKDM4ETHRBALDH1A1PDGFRB | |
| SCHEMBL1328701 | 0.68 | TTBK1 (0.51) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391774-A1 | Novel Compounds | AC IMMUNE SA (CH) | 2023-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391774-A1 | Novel Compounds | MAPT, PSEN2, PSEN1 | MAPT 1/4885KDM4E 4326/4885THRB 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.