Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 8/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24216492 | 1.00 | HRH3 (0.51) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL24215860 | 0.88 | LMNA (0.57) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL30409169 | 0.88 | LMNA (0.57) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL24216507 | 0.85 | HTR6 (0.61) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL30410475 | 0.85 | HTR6 (0.61) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL24216324 | 0.82 | DRD2 (0.63) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL30408006 | 0.82 | DRD2 (0.63) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL19252887 | 0.80 | HRH3 (0.54) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL13050952 | 0.80 | HRH3 (0.56) | HRH3BCHECYP2D6DRD4DRD2 | |
| SCHEMBL31217232 | 0.80 | EGFR (0.56) | HRH3BCHECYP2D6DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |