Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912333 | 0.91 | LMNA (0.65) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28560080 | 0.89 | MAPT (0.64) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28558521 | 0.82 | KDM4E (0.72) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28571382 | 0.82 | LMNA (0.54) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28566162 | 0.82 | MAPT (0.64) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28565202 | 0.80 | MEN1 (0.57) | MAPTPOLBLMNAKDM4EHCAR3 | |
| SCHEMBL11957598 | 0.78 | MAPT (0.72) | MAPTPOLBPDE7AALDH1A1SMN1; SMN2 | |
| SCHEMBL24704031 | 0.76 | KDM4E (1.00) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL28563175 | 0.76 | LMNA (0.59) | MAPTPOLBL3MBTL1LMNAKDM4E | |
| SCHEMBL11693391 | 0.75 | ALDH1A1 (0.66) | MAPTPOLBLMNAHCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638909-A | Compounds with antibacterial activity | 香港理工大学 | 2021-04-09 | — | — | CN | disclosed |