Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 11/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964514 | 0.84 | KDM4E (0.52) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL11359600 | 0.81 | ALDH1A1 (0.46) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL28072438 | 0.81 | KDM4E (0.46) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL30987223 | 0.80 | MAPT (0.60) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL28563540 | 0.80 | MAPT (0.60) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL24566449 | 0.79 | MAPT (0.47) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL28072437 | 0.77 | KDM4E (0.46) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL11352247 | 0.77 | KDM4E (0.42) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL28167685 | 0.77 | EPAS1 (0.57) | EPAS1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL3979992 | 0.76 | LSS (0.48) | MAPTLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |